Infanticide.
I list this because I'm still reeling from the idea that anyone, ANYONE, could justify denying medical care to any living infant.
I weep when I think of the millions who would say "Yes, infanticide is OK" and cast their votes for Obama. For me, it's the watershed, non-partisan issue. Am I a one issue candidate? No. Could I support a "pro-choice" candidate for President? Yes, given a compelling array of other outstanding qualities (for example, excellent on national defense). But, I could not support a candidate that was pro-late term abortion, which are never medically necessary for the mother's health. But Barack Obama goes even further, condoning at a stroke the killing of the baby and extreme parental neglect.
This extreme position indicates something very profound about his own character, and his deeply held beliefs. He voted against the Born Alive Infant Protection Act three times, including one time when the "neutrality clause" was inserted to ensure that a woman's right to an abortion was protected.
This is change I don't believe in.